| Acronym | Definition |
| SOP | Standard Operating Procedure |
| SOP | Separation of Powers |
| SOP | Sex on Phone |
| SOP | State of Practice (various organizations) |
| SOP | Soprano |
| SOP | Statement Of Position |
| SOP | Sisters of Providence (various locations) |
| SOP | Summary of Progress (education; various locations) |
| SOP | Statement Of Purpose |
| SOP | Stock Option Plan |
| SOP | Standards of Participation (California) |
| SOP | Statement of Participation |
| SOP | School of Pharmacy |
| SOP | Survey of Pakistan (est. 1947) |
| SOP | Solicitation of Proposals (various organizations) |
| SOP | Statement of Principle (various locations) |
| SOP | Standard of Perfection (American Poultry Association) |
| SOP | String of Purls (blog and shop; Omaha, NE) |
| SOP | Sales Order Processing |
| SOP | Senior Outreach Program (various locations) |
| SOP | Service of Process |
| SOP | Small Outline Package |
| SOP | Standing Operating Procedure |
| SOP | Service Orthodoxe de Presse |
| SOP | Stock Ownership Plan (various organizations) |
| SOP | Standard Operating Platform (Best Buy) |
| SOP | Super Operator |
| SOP | Server Operator |
| SOP | Subject Oriented Programming |
| SOP | Start of Production |
| SOP | Service Object Pair |
| SOP | Scope of Practice (EMS) |
| SOP | School of Psychology |
| SOP | State Of Play |
| SOP | Seat of Pants |
| SOP | Standards of Performance |
| SOP | State Operating Permit (various locations) |
| SOP | Sum of Products (Boolean expressions and logic gates) |
| SOP | Secretaria de Obras Publicas |
| SOP | Surgical Oncology Program (Canada) |
| SOP | Standard Operational Procedure |
| SOP | Start Of Production (automobile industry) |
| SOP | Son of Perdition (Christianity) |
| SOP | Street Opening Permit (various locations) |
| SOP | Standard of Practice |
| SOP | Same Origin Policy (browser model) |
| SOP | Student Operated Press |
| SOP | Sense of Place |
| SOP | Significant Other Person |
| SOP | System-On-Package |
| SOP | Student Orientation Program (various schools) |
| SOP | Streaming Over P2P (Peer to Peer) |
| SOP | Safe Operating Procedure |
| SOP | System.out.println (Java) |
| SOP | Signal Output Port (computing) |
| SOP | Sum of the Parts (financial valuation method) |
| SOP | State of Polarization |
| SOP | Start of Packet |
| SOP | Sulfate of Potash (potassium sulfate) |
| SOP | Senza Obbligo di Prescrizione (Italian: Over The Counter) |
| SOP | Sorted Office Paper |
| SOP | School Organisation Plan (UK education) |
| SOP | Senior Officer Present |
| SOP | Stuck Open |
| SOP | Seeds of Peace |
| SOP | Super-Operator (IRC channels) |
| SOP | Standard Operating Policies |
| SOP | Service Oriented Process |
| SOP | Service Object Pair (digital imaging) |
| SOP | Sons of the Patriots (gaming clan) |
| SOP | Service Oriented Programming (AMIS) |
| SOP | Subject-Oriented Programming |
| SOP | Stochastic Orthogonal Polynomial (mathematics) |
| SOP | System Operating Procedures |
| SOP | Son of Peter (band) |
| SOP | Science Operations Plan |
| SOP | Sndrome del Ovario Poliquistico (medical) |
| SOP | Security Operating Procedures |
| SOP | Service Order Processing |
| SOP | Start of Project |
| SOP | Secure Online Payment |
| SOP | Sequential Ordering Problem |
| SOP | Sensory Organ Precursors |
| SOP | Space Operations Squadron (USAF) |
| SOP | Sales Operation Planning |
| SOP | Security of Payments |
| SOP | Secondary Oxygen Pack (US NASA) |
| SOP | Socit Odontologique de Paris (French: Paris Odontology Society) |
| SOP | Site Operating Plan |
| SOP | Standard of Procedure |
| SOP | Scholarship Opportunities Program |
| SOP | Southern Pines, NC, USA - Pinehurst (Airport Code) |
| SOP | Special Order Parts (materials procurement) |
| SOP | Stock Option Price |
| SOP | Solder on Pad (semiconductor process) |
| SOP | Sexual Offender Program |
| SOP | State of the Parks Report (Canada) |
| SOP | Seagrass Outreach Partnership |
| SOP | Safe Operating Practice |
| SOP | Spawn of Possession (band) |
| SOP | Shown on Plans (blueprints) |
| SOP | Service Offering Portfolio |
| SOP | Special Operations Program |
| SOP | Syndicat des Oprateurs Postaux (French: Union of Postal Operators) |
| SOP | Study Organization Plan |
| SOP | System Operations Panel |
| SOP | Subsystem Operating Program (NASA, CEV Space Capsule) |
| SOP | Shared Object Parser (Macromedia) |
| SOP | Sub Operator |
| SOP | Support Oriented Processes (quality management) |
| SOP | Starfire Optical Range |
| SOP | Streaked Optical Pyrometry |
| SOP | Standard Operating Power |
| SOP | Short Optical Pulse |
| SOP | Sobrang Ok Pare (Philippine TV program) |
| SOP | Space-based Observation Panel |
| SOP | Standards of Payments |
| SOP | Spacecraft Operation Procedure |
| SOP | Seal Oil Pump |
| SOP | Setting Out Point (construction) |
| SOP | Sprint Online Presenter |
| SOP | Source Open Failure Mode |
| SOP | Segment Originators PLA (Plain Language Address) |
| SOP | System Optimization Plan |
| SOP | Shoot-Out Points (hockey standings) |
| SOP | Stupid Operating Procedures |
| SOP | System Operating Process |
| SOP | Ship Operational Program |
| SOP | Solid Object Printing |
| SOP | Strategic Operating Platform |
| SOP | Sterile Ophthalmic Prepa |