Oncolytics Biotech Inc T.ONC

Beam Therapeutics Phase 1 CAR-T study placed on hold by FDA

[Noteable]

August 01, 2022 - Beam Therapeutics’ leukemia and lymphoma CAR-T therapy has been stopped in its tracks by the FDA after a clinical hold was placed on the new drug application.

Beam. still a pre-clinical drug development company, signed a bio-bucks licensing deal with Pfizer in January 2022 to work on gene editing therapies, with $300 million upfront and $1.35 billion possibly available down the line in milestones.

Beam is trying to move BEAM-201 into human study for relapsed/refractory T-cell acute lymphoblastic leukemia and T-cell lymphoblastic lymphoma. 

Shares of Beam fell over 10% in premarket trading to $56.25, compared to a close on Friday of $62.98.

https://www.fiercebiotech.com/biotech/beams-light-scatters-fda-blocks-phase-1-study-lymphoma-car-t

https://beamtx.com/pipeline/

[Noteable]

Beam Therapeutics has a market cap of approximately US$4.5 Billion notwithstanding that the company still is a pre-clinical stage company.

[Noteable]

August 30, 2022 - "The FDA’s concerns about BEAM-201 are multi-faceted but include questions about the company’s gene-editing technology."  "Evidently, the company’s editing aspirations have been more difficult to execute than expected. In addition to addressing regulators’ questions, the company reported ealier in August that more edits than expected are necessary to

[Noteable]

Shares of Beam Therapeutics traded at USD$ 62.98 on Friday and trade at approximately USD$ 61.00 today. Beam Therapeutics has a market cap of USD$ 4.5 Billion.

[inthno]

And you wonder why people get so pissed off with our share price sitting where it is when a pre-clinical company has a market value of 4.5 billion. Kinda shows you that something is either not right with onc or no one really cares. Hopefully that will change soon enough and also hoping that we will have more clarity with the release of the quarterly. I would be more than happy with a buyout in the

[canadafan]

Great points. The market value of ONC ( presently), is a fraction of it peer market potential. One of a few things can & eventually will happen. 1. the Pela technology will prove out & market value will adjust upward. 2. the Pela technology will not prove out & justify the existing value. Simple logic

[Noteable]

Once again Canadfan's logic is flawed. See my post below given the value of the pre-clinical assets described in that referenced post. 

[canadafan]

Not sure what flaw you are talking about? I agree with your " manipulation" theory 100%. Onc shares are not low because of any failed trial or real issue at all. however, because of where things are. for example the recent Goblet results alone, should move Onc SP well into the $12-$15ps range. has not yet? because of a well orhastrated team, working to keep the SP down. To fix that, a

[Noteable]

You Canadfan wrote: One of a few things can & eventually will happen. 1. the Pela technology will prove out & market value will adjust upward. 2. the Pela technology will not prove out & justify the existing value. Simple logic No -- not simple logic -- flawed logic for reasons that I already provided in the 2 preclinical examples involving Trillium and Beam Therapeutics whereby in

[Noteable]

Excuse the syntax errors in the previous post but its late and I've had no time to proof read my response to Canadafan before posting it. Have a good night. 

[Lesalpes29]

Manipulation is one thing but... lack of interest by the market is the responsability of management. It's a big miss by the board. Recent events like insiders transactions and the addition of Mr. Parsons are positives. We need more it seems, to get institutions interest.

[Snowdrift]

Noteable, you made some good points here and perhaps Canafan's logic is, in fact, flawed.  However, that you find his post "SUSPICIOUS" is ridiculous!!  I rarely comment, but I've been watching the board for a long tme and I've never found Canadafan suspicious in the slightest.  Maybe you're overreacting a little?

[Noteable]

Anyone who admits they are a swing trader and who then goes on to repearedly profess something that is flawed or specious, can only be viewed as "suspicious" in the real world today.

[canadafan]

" swing trader"? perhaps you are over reacting. I did say I have owned Onc on & off since 1998. The bulk of my holdings have been since when Matt took over for retired Brad T.  lost track of dates, but I believe 2017.  when I " bought back in" That was not long before the A.N. Announcement. I have bought more, last few months, notably when it was bellow

[cardu]

I'm with you 100% canadafan.

[Noteable]

Taken from the yahoo message board posted in January 2022 .. " .. those hedge funds and investment banks who unscrupulously trade in this stock have been notorious for using paid employees to bash away at the stock, its shareholders, and its management while wildly working the price and trading action to accumulate as much stock possible in advance of an acquisition." The above