Oncolytics Biotech Inc T.ONC

Novartis returns anti-PD1 to Chinese based company BeiGene

[Noteable]

https://www.biospace.com/article/releases/beigene-strengthens-global-portfolio-and-regains-full-rights-from-novartis-for-anti-pd-1-antibody-tevimbra-tislelizumab-/

[Noteable]

September 19, 2023 - The news marks the end of a second immuno-oncology partnership between the two companies after they parted ways on BeiGene’s anti-TIGIT candidate ociperlimab about two months ago. In a statement to Fierce Pharma, Novartis said a changing PD-1 inhibitor landscape led to the decision to terminate the tislelizumab agreement. [Tislelizumab (BGB-A317) is a humanized IgG4

[Noteable]

“This decision will provide Novartis with greater flexibility for development of its unique, potentially transformational pipeline assets, notably in markets where there are already approved PD-1 therapies in desired indications that can support development of our novel IO combination programs.”  Maybe cash- rich Novartis is thinking of acquiring ONCYs pelareorep to be combined

[Noteable]

https://www.cantor.com/our-company/conferences/global-healthcare-conference-2023/

[Noteable]

In case anyone missed this ... [ ONCYs Bracelet-1 study demonstrated that a non-silenced Fc receptor site on a PD-1 checkpoint inhibitor like avelumab (Bavencio) for example, resulted in significantly reduced efficacy of that PD-1 checkpoint inhibitor. avelumab has a native Fc region that retains FcγR binding capability as does tislelizumab] -- https://pubmed.ncbi.nlm.nih.gov/34484871/

[13X2413]

Can't they come up with something better than a fireside chat? Opening doesn't look promising. 

[Lesalpes29]

13x... you said not a long timo ago that you sold... Thank you to continue to post here to help the real longs here to understand the science! Euh... You can write to PanCan people too, they are lost like us! GLTAL 

[13X2413]

You think I'd be posting here if I sold. Still long, that's why I'm p*ssed.  Still hoping for a miracle. 

[Lesalpes29]

OK, smile it will be a green day... probably!