Theralase Technologies Inc. V.TLT

Questions without answers

[consultant99]

Theralase says the FDA defined a complete clinical dataset on approx 20 to 25 patients enrolled, treated and assessed who demonstrate significant safety and efficacy outcomes for BTD.

With 24 patients completed why is the company waiting months for 1 more patient? Regardless of the last scan result 1433 will exceed the Keytruda results at 450 days. 

It looks like 4 patients were treated in the last three months. 

As of May 30th we had a CR of 17 and PR of 8 and at the end of Aug a CR of 19 and PR of 6 for scans at 90 days. There were 4 scans pending May 30th so what happened to those patients; N/R, or no scans done? Trying to understand the results isn't easy when the company continues to change their results tables.

The company has 12 sites in operation although up to 15 were contemplated as part of the trial study. Will they expand to 15? Have all sites treated patients? This trial is taking forever to complete and we are only 35% of the way through treating 120 patients.

The management notes provide no guidance as to the company's capital requirements in 2023. There really is no discussion of the vaccine opportunity outside of the current Covid animal testing. While the company has executed the SRA with UM where does the company see this opportunity going in 2023 and beyond?

I think the company is sitting on some great technology but the stock is at $0.30/share...

[Rumpl3StiltSkin]

If they wait 90 days that Total Response 360 day column will shift, mostly, to the 450 day column. So the CR numbers will be much better...  Also, they will have Covid data out between now and then to deal sith SP, IMO.

[consultant99]

Waiting three months will bring three patients from the 360 day scan column to the 450 day scan column. Agreed. However the company is only going to submit the data for the first 25 patients. That 25th patient could be NR CR or PR. Getting BTD is a binary outcome based on the application - yes or no. From everything the company has been telling shareholders we meet the requirements based on the

[Rumpl3StiltSkin]

They may not wait that long, so say patient #25s data is a couple weeks away, they could submit it then, the numbers getting better only helps the cause as the FDA gives TLTs BTD a serious look. Likewise the AA as we move into next year.

[Legit62]

Feeling same way Rump, i said before i bet we are applying before mid 4th quarter the results are only going to get better with the optimized group, plus we have other indications moving foward, and we will get big boost from covid indication as well, im grabbing more shares every chance i get