- Dr. Larrieux brings significant experience managing analytical development quality control of immunotherapies
to treat cancer and small molecule therapies at pharmaceutical and biotechnology organizations
NEW YORK, Dec. 19, 2016 (GLOBE NEWSWIRE) -- Actinium Pharmaceuticals, Inc. (NYSE MKT:ATNM) ("Actinium" or "the
Company"), a biopharmaceutical company developing innovative targeted therapies for cancers lacking effective treatment options,
announced today that Jeannine Larrieux, Ph.D. has been appointed Director of Analytical Development. Dr. Larrieux will be
responsible for analytical assay development, conducting biologics license application (BLA) and investigational new drug (IND)
enabling studies, authoring CMC analytical sections for BLA and IND filings and supporting both internal and external quality
assurance (QA) and quality control (QC) efforts.
“Dr. Larrieux is an accomplished analytical professional who is bringing over 20 years of highly relevant
industry experience in matters related to regulatory submissions, project management and QA/QC to Actinium,” said Sandesh Seth,
Actinium’s Executive Chairman. “Dr. Larrieux is yet another invaluable addition to the Actinium team that will contribute
enormously to the development of our clinical programs Iomab-B and Actimab-A as well as future clinical programs we hope to unveil
in the near future.”
Dr. Larrieux joins Actinium following analytical consulting assignments in the U.S. and Europe. Prior to this,
she was Head of AS&T at Novartis where she focused on cell therapy products aimed to treat acute lymphoblastic leukemia (ALL)
and chronic lymphocytic leukemia (CLL). Prior to Novartis, Dr. Larrieux was Laboratory Manager at Dendreon Corporation where she
supported Phase 3 and Phase 4 clinical studies. In addition, Dr. Larrieux has worked at Pfizer, Purdue Pharma and Wyeth in
analytical roles.
Dr. Larrieux earned her Ph.D. in Material Chemistry from Polytechnic Institute of NYU, an M.S. degree in
Chemistry from Polytechnic University and a BS.c. degree in Chemistry from State University of HAITI (PAP). In addition, she is a
member of the Regulatory Affairs Professionals Society (RAPS) and a member of the American Society for Quality (ASQ).
About Actinium Pharmaceuticals, Inc.
Actinium Pharmaceuticals, Inc. is a biopharmaceutical company developing innovative targeted therapies for
patients with cancers lacking effective treatment options. Actinium's proprietary platform utilizes monoclonal antibodies to
deliver radioisotopes directly to cells of interest in order to kill those cells safely and effectively. The Company's lead product
candidate Iomab-B is designed to be used, upon approval, in preparing patients for a hematopoietic stem cell transplant, commonly
referred to as bone marrow transplant. A bone marrow transplant is often the only potential cure for patients with blood-borne
cancers but the current standard preparation for a transplant requires chemotherapy and/or total body irradiation that result in
significant toxicities. Actinium believes Iomab-B will enable a faster and less toxic preparation of patients seeking a bone marrow
transplant, leading to increased transplant success and survival rates. The Company is currently conducting a single pivotal
150-patient, multicenter Phase 3 clinical study of Iomab-B in patients with relapsed or refractory acute myeloid leukemia (AML) age
55 and older. The Company's second product candidate, Actimab-A, is currently in a multicenter open-label, 53-patient Phase 2 trial
for patients newly diagnosed with AML age 60 and over. Actimab-A is being developed to induce remissions in elderly patients with
AML who lack effective treatment options and often cannot tolerate the toxicities of standard frontline therapies. Actinium is also
utilizing its alpha-particle immunotherapy (APIT) technology platform to generate new drug candidates based on antibodies linked to
the element Actinium-225 that are directed at various cancers that are blood-borne or form solid tumors. Actinium Pharmaceuticals
is based in New York, NY. To learn more about Actinium Pharmaceuticals, please visit www.actiniumpharma.com and to follow @ActiniumPharma on Twitter please visit, www.twitter.com/actiniumpharma.
Forward-Looking Statements for Actinium Pharmaceuticals, Inc.
This news release contains "forward-looking statements" as defined in the Private Securities Litigation Reform
Act of 1995. These statements are based on management's current expectations and involve risks and uncertainties, which may cause
actual results to differ materially from those set forth in the statements. The forward-looking statements may include statements
regarding product development, product potential, or financial performance. No forward-looking statement can be guaranteed and
actual results may differ materially from those projected. Actinium Pharmaceuticals undertakes no obligation to publicly update any
forward-looking statement, whether as a result of new information, future events, or otherwise.
Contact: Actinium Pharmaceuticals, Inc. Steve O'Loughlin Vice President, Finance and Corporate Development soloughlin@actiniumpharma.com