TEL AVIV, Israel, Jan. 16, 2018 /PRNewswire/ -- Cellect
Biotechnology Ltd. (Nasdaq: APOP), a developer of a novel stem cell selection technology, announced that it has signed an
agreement with the Hadassah Medical Center to conduct clinical trials on cancer patients in Cellect's ongoing Phase I/II study.
The study at Hadassah will be conducted under Prof. Polina Stefenski, the Principal Investigator of the site at Hadassah.
Furthermore, following the recently announced positive interim results in the Phase I/II clinical trial with the first group of
patients treated at the Rambam Medical Center, Cellect received approval from the independent Data and Safety Monitoring Board
(DSMB) to escalate ApoGraft™ FasL protein dosage (Cellect's main active ingredient in ApoGraft™) to 25 ng/ml and enroll three
additional patients for the clinical trial.
Dr. Shai Yarkoni, Cellect's CEO said, "Stem cells are the key raw material for the emergence of
Cell Therapy into the 21st century as the new standard for well-being. We believe Cellect's innovative technology
paves the way to make sure quality stem cells are available for mass usage on a global basis."
About Regenerative Medicine and Cell Therapy
Regenerative medicine is a novel approach using cells and tissues to replace or regenerate human cells, tissues or organs in a
wide variety of medical indications. This could be achieved by either stimulating the body to use its own repair mechanisms to
heal tissues or organs, or by growing tissues and organs in the laboratory and transplanting them into the patient.
Stem cells play a major role in the achievement of the extraordinary potential results in regenerative medicine. In cell
therapies they can be injected to reconstitute the entire blood system in bone marrow transplantations. Alternatively, their
injection can supply the necessary biologically active molecules to induce the patients' own cells to regain normal function, as
used in immunomodulation therapy. In tissue engineering, where entire organs like the retina, bone, cartilage or the skin may be
replaced, stem cells are the starting material for the growth of such tissues in the laboratory. Moreover, in tissue engineering
an artificial system might be created by inducing cells to perform certain biochemical functions lost due to disease (e.g.,
artificial pancreas or liver).
Regenerative medicine using cellular therapy in combination with new technologies like tissue engineering and gene transfer
can be used in a virtually unlimited number of indications. The most frequently used cells are hematopoietic stem cells (HSC) due
to their capability to reproduce the entire blood system in blood cancer and hematological disorders. Mesenchymal stem cells,
which have the capability to differentiate to a large number of tissue types like bone, cartilage, fat, heart muscle and more,
are of growing importance with a large number of clinical trials ongoing. Potential applications of cell therapies include
treating cancers, autoimmune disease, urinary problems and infectious disease, rebuilding damaged cartilage in joints, repairing
spinal cord injuries, improving a weakened immune system, and helping patients with neurological disorders.
About Cellect Biotechnology Ltd.
Cellect Biotechnology (NASDAQ: APOP) has developed a breakthrough technology for the selection of stem cells from any given
tissue that aims to improve a variety of stem cell-based therapies.
The Company's technology is expected to provide research, hospitals and pharma companies with the tools to rapidly isolate
stem cells in quantity and quality allowing stem cell-based treatments and procedures in a wide variety of applications in
regenerative medicine. The current clinical trial is aimed at bone marrow transplantations in cancer treatment.
Forward Looking Statements
This press release contains forward-looking statements about the Company's expectations, beliefs and intentions.
Forward-looking statements can be identified by the use of forward-looking words such as "believe", "expect", "intend", "plan",
"may", "should", "could", "might", "seek", "target", "will", "project", "forecast", "continue" or "anticipate" or their negatives
or variations of these words or other comparable words or by the fact that these statements do not relate strictly to historical
matters. For example, forward-looking statements are used in this press release when we discuss Cellect's intent regarding the
effects of the ApoGraft™ transplantation and Cellect's aims and expectations regarding the future of its ApoGraft™ technology and
stem cell based regenerative medicine. These forward-looking statements and their implications are based on the current
expectations of the management of the Company only, and are subject to a number of factors and uncertainties that could cause
actual results to differ materially from those described in the forward-looking statements. In addition, historical results or
conclusions from procedures, scientific research and clinical studies do not guarantee that future results would suggest similar
conclusions or that historical results referred to herein would be interpreted similarly in light of additional research or
otherwise. The following factors, among others, could cause actual results to differ materially from those described in the
forward-looking statements: changes in technology and market requirements; we may encounter delays or obstacles in launching
and/or successfully completing our clinical trials; our products may not be approved by regulatory agencies, our technology may
not be validated as we progress further and our methods may not be accepted by the scientific community; we may be unable to
retain or attract key employees whose knowledge is essential to the development of our products; unforeseen scientific
difficulties may develop with our process; our products may wind up being more expensive than we anticipate; results in the
laboratory may not translate to equally good results in real clinical settings; results of preclinical studies may not correlate
with the results of human clinical trials; our patents may not be sufficient; our products may harm recipients; changes in
legislation; inability to timely develop and introduce new technologies, products and applications, which could cause the actual
results or performance of the Company to differ materially from those contemplated in such forward-looking statements. Any
forward-looking statement in this press release speaks only as of the date of this press release. The Company undertakes no
obligation to publicly update or review any forward-looking statement, whether as a result of new information, future
developments or otherwise, except as may be required by any applicable securities laws. More detailed information about the risks
and uncertainties affecting the Company is contained under the heading "Risk Factors" in Cellect Biotechnology Ltd.'s Annual
Report on Form 20-F for the fiscal year ended December 31, 2016 filed with the U.S. Securities and
Exchange Commission, or SEC, which is available on the SEC's website, www.sec.gov and in the Company's period filings with the SEC.
Contact
Cellect Biotechnology Ltd.
Eyal Leibovitz, Chief Financial Officer
www.cellect.co
+972-9-974-1444
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SOURCE Cellect Biotechnology Ltd.