OTTAWA, March 04, 2019 (GLOBE NEWSWIRE) -- Tetra Bio-Pharma Inc. ("Tetra" or
the "Company") (TSX-V: TBP) (OTCQB: TBPMF), a global leader in cannabinoid-derived drug development and
discovery, is pleased to announce completion of the first double-blind, randomized and placebo-controlled Phase 2 clinical trial of
cannabis oil capsules. The trial evaluated the safety and efficacy of different doses and ratios of medical cannabis oil comprised
of THC and CBD, for the treatment of uncontrolled chronic pain in cancer and non-cancer patients.
The Phase 2 trial was conducted by Montreal-based Santé Cannabis, Quebec's first clinical research
organization specializing in cannabis and cannabinoids for medical purposes. Dr. Antonio Vigano, and his colleagues at Santé
Cannabis, designed this study to obtain clinical data on the safety and potential efficacy of various cannabis oils used in the
practice of medicine under the Cannabis regulations.
During the next 3 months, Santé Cannabis will study the data and submit a scientific manuscript for publication addressing key
outcomes from the trial:
- Safety and tolerability data, such as side effects, associated with the approach used in this study;
- Preliminary efficacy data on the three different ratios of THC and CBD used; and
- Preliminary data on the minimal effective dose of each cannabis oil.
"This study will provide evidence-based data on medical cannabis for chronic pain," said Dr. Antonio
Vigano, Research Director of Santé Cannabis and McGill University Associate Professor in the Department of Oncology. "For
many patients, under careful monitoring, cannabis oil can potentially reduce or even eliminate the need for other pharmacological
medications. The outcome of this study will support clinicians to better understand dosing and titration of medical cannabis in
cancer and non-cancer patients. Our data will encourage researchers to pursue deeper studies to quantify real benefits and
potential risks of natural cannabinoids as a complementary therapeutic approach across larger populations."
According to Dr. Guy Chamberland, Tetra's CEO and CSO, "This study is the first to investigate encapsulated
medical cannabis oil for the management of chronic pain. The analysis of key outcomes will provide Tetra Bio-Pharma with important
scientific data on the optimal effective dose range for patients suffering from these conditions. We are pleased to continue to
support university-based studies such as this, which will help guide some of Tetra’s key drug development programs in chronic pain,
oncology and ophthalmic. The Corporation is dedicated to developing prescription cannabinoid-derived drugs for the treatment
of uncontrolled cancer and non-cancer pain and to reduce the need for opioids.”
About Tetra Bio-Pharma:
Tetra Bio-Pharma (TSX-V: TBP) (OTCQB: TBPMF) is a biopharmaceutical leader in cannabinoid-based drug discovery and
development with a Health Canada authorized, and FDA reviewed, clinical trials aimed at bringing novel prescription drugs and
treatments to patients and their healthcare providers. The Company has several subsidiaries engaged in the development of an
advanced and growing pipeline of Bio Pharmaceuticals, Natural Health and Veterinary Products containing cannabis and other
medicinal plant-based elements. With patients at the core of what we do, Tetra Bio-Pharma is focused on providing rigorous
scientific validation and safety data required for inclusion into the existing bio pharma industry by regulators, physicians and
insurance companies.
For more information visit: www.tetrabiopharma.com
Source: Tetra Bio-Pharma
Neither the TSX Venture Exchange nor its Regulation Services Provider (as that term is defined in the
policies of the TSX Venture Exchange) accepts responsibility for the adequacy or accuracy of this release.
Forward-looking statements
Some statements in this release may contain forward-looking information. All statements, other than of historical fact, that
address activities, events or developments that the Company believes, expects or anticipates will or may occur in
the future (including, without limitation, statements regarding: the anticipated benefits of the Proposed Transaction for Tetra;
completion and expected timing of the Proposed Transaction; whether the terms of the Proposed Transaction will be as described in
this press release; whether the Proposed Transaction will be successful; the receipt of required regulatory approvals (including
stock exchange) in respect of the Proposed Transaction)are forward-looking statements. Forward-looking statements are generally
identifiable by use of the words "may", "will", "should", "continue", "expect", "anticipate", "estimate", "believe", "intend",
"plan" or "project" or the negative of these words or other variations on these words or comparable terminology. Forward-looking
statements are subject to a number of risks and uncertainties, many of which are beyond the Company's ability to control or
predict, that may cause the actual results of the Company to differ materially from those discussed in the forward-looking
statements. Factors that could cause actual results or events to differ materially from current expectations include, among other
things, without limitation, the inability of the Company to obtain sufficient financing to execute the Company's business plan;
competition; regulation and anticipated and unanticipated costs and delays, the success of the product mentioned in this release,
the success of the Company's research and development strategies, the applicability of the discoveries made therein, the successful
and timely completion and uncertainties related to the regulatory process including the applications for Orphan Drug Designation,
the timing of clinical trials, the timing and outcomes of regulatory or intellectual property decisions and other risks disclosed
in the Company's public disclosure record on file with the relevant securities regulatory authorities. Although the Company has
attempted to identify important factors that could cause actual results or events to differ materially from those described in
forward-looking statements, there may be other factors that cause results or events not to be as anticipated, estimated or
intended. Readers should not place undue reliance on forward-looking statements. The forward-looking statements included in this
news release are made as of the date of this news release and the Company does not undertake an obligation to publicly update such
forward-looking statements to reflect new information, subsequent events or otherwise unless required by applicable securities
legislation.
For further information, please contact Tetra Bio-Pharma Inc.
Robert (Bob) Bechard
Executive Vice President, Corporate Development and Licensing
514-817-2514
Investors@tetrabiopharma.com
Media Contact:
Carol Levine
Carol.levine@energipr.com
514-288-8500 ext. 226
Marissa Zanti
Marissa.zanti@energipr.com
416-425-9143 ext. 204
![Primary Logo](https://resource.globenewswire.com/media/2c4e6b53-8422-4ab8-b82e-bdcf305f6c17/small/tetra-150-jpg.jpg)