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ProMIS Neurosciences Inc PMN

ProMIS Neurosciences Inc. is a development stage biotechnology company. The Company is focused on generating and developing antibody therapeutics selectively targeting toxic misfolded proteins in neurodegenerative diseases such as Alzheimer’s disease (AD), amyotrophic lateral sclerosis (ALS) and multiple system atrophy (MSA), an alpha-synucleinopathy. Its proprietary target discovery engine applies a thermodynamic, computational discovery platform - ProMIS and Collective Coordinates - to predict novel targets known as Disease Specific Epitopes on the molecular surface of misfolded proteins. Using this approach, the Company is developing novel antibody therapeutics for AD, ALS and MSA. Its product portfolio includes PMN310 / Amyloid-beta, PMN267 / TDP-43, and PMN442 / Alpha-synuclein. The Company plans to investigate additional synucleinopathies, including Parkinson's disease (PD) and dementia with Lewy bodies (DLB). Its wholly owned subsidiary is ProMIS Neurosciences (US) Inc.


NDAQ:PMN - Post by User

Bullboard Posts
Comment by Gbathaton Jul 04, 2018 9:05am
166 Views
Post# 28266192

RE:RE:RE:Untangling the Beta-Amyloid Oligomers

RE:RE:RE:Untangling the Beta-Amyloid Oligomersfrom pg 23 of analyst report:

Our discounted cash flow (DCF) model uses a 15% discount rate and a 2% terminal decline rate. Ultimate probability of success is estimated to be 7%.49 This is a downward adjustment to Phase I success rates of between 10% and 14%50,51. This recognizes that manufacturing efforts have started but have not yet been fully implemented and that the IND application has not yet been submitted or cleared. Our model reflects dilution from exercise of options and warrants. Based on the assumptions described and after adjusting for shares, restricted stock and options outstanding, we generate a target price of CAD$7.00.


As I read it, it seems to imply that there is a 7% chance of success based on historical analysis of similar companies.  This is multiplied then by the target price of the successful company ($100 pps on a fully diluted basis w/ warrants exercised) to get a current valuation of $7 canadian pps.

pg 23 of the report explains in further detail, including estimates of market size, share, operating costs, licensing arrangements, etc

bottom line: I am interpreting this $7 valuation as what they think the company is worth today and where the stock is heading in the next 12 months.  As that probability of success goes up (with more progress) or down, then the valuation will change proportionally.

just my opinions/interpretations.  

I currently have 18,000 shares and probably won't buy more or sell any for a while.
Bullboard Posts