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ProMIS Neurosciences Inc PMN

ProMIS Neurosciences Inc. is a development stage biotechnology company. The Company is focused on generating and developing antibody therapeutics selectively targeting toxic misfolded proteins in neurodegenerative diseases such as Alzheimer’s disease (AD), amyotrophic lateral sclerosis (ALS) and multiple system atrophy (MSA), an alpha-synucleinopathy. Its proprietary target discovery engine applies a thermodynamic, computational discovery platform - ProMIS and Collective Coordinates - to predict novel targets known as Disease Specific Epitopes on the molecular surface of misfolded proteins. Using this approach, the Company is developing novel antibody therapeutics for AD, ALS and MSA. Its product portfolio includes PMN310 / Amyloid-beta, PMN267 / TDP-43, and PMN442 / Alpha-synuclein. The Company plans to investigate additional synucleinopathies, including Parkinson's disease (PD) and dementia with Lewy bodies (DLB). Its wholly owned subsidiary is ProMIS Neurosciences (US) Inc.


NDAQ:PMN - Post by User

Bullboard Posts
Comment by Gbathaton Feb 11, 2020 7:51pm
88 Views
Post# 30677373

RE:RE:ban2401 comparison

RE:RE:ban2401 comparisonIt is interesting to read all the press about Roche ph3 failure announcement, which is predicted by the promis hypothesis, as being a negative result for biogen.  Lots of skepticism due to many plaque targeting failures.

Yes, we want biogen to have partial success, thereby setting up pmn.  My question is more about why aducanumab is used as our benchmark rather than ban2401, given that ban2401 appears to be slightly better between the two, based on recent presentations and reports.

Dr Goldstein verbally indicated that the two are basically similar.  I would just like to see some dot blot and spr data if they have it.

I am still all in on pmn and a huge fan. Just trying to do all the due diligence I can.
Bullboard Posts