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Antibe Therapeutics Inc(Pre-Merger) T.ATE


Primary Symbol: ATBPF

Antibe Therapeutics Inc. is a clinical-stage biotechnology company. The Company is leveraging its hydrogen sulfide (H2S) platform to develop therapies to target inflammation arising from a range of medical conditions. The Company’s pipeline includes assets that seek to overcome the gastrointestinal ulcers and bleeding associated with nonsteroidal anti-inflammatory drugs (NSAIDs). Its lead drug, otenaproxesul, is in clinical development as an alternative to opioids and NSAIDs for acute pain. Its second pipeline drug, ATB-352, is being developed for a specialized pain indication. The Company also focuses on inflammatory bowel disease (IBD). Otenaproxesul combines a moiety that releases hydrogen sulfide with naproxen, a non-steroidal, anti-inflammatory drug. ATB-352 is an H2S-releasing derivative of ketoprofen, a potent NSAID commonly prescribed for acute pain. Its IBD candidates are being designed to maintain the efficacy, safety, and pharmacokinetic properties of ATB-429.


GREY:ATBPF - Post by User

Comment by WalkOverTheStrton May 09, 2021 12:24pm
242 Views
Post# 33161957

RE:ATE.TO Drug Pipeline = $50B plus

RE:ATE.TO Drug Pipeline = $50B plusThe hydrogen sulfide is not a "platform" until it shows success in at least two human studies. The HS2 IP is not a proven platform and therefore the market will give little value to the preclinical pipeline.  Antibe could and will strengthen it's negotations once 352 has at a min PH1 positive results. We should all hope Antibe does not delay expanding 352 and / or other preclinicial drugs as the human data needs to be presented / abosrbed by the market. I'd suggest looking at RNAI and specifically Alny and ARWR (going thru this case with their outside the liver drugs ENAC/HIF2 - little credit / value although these drugs could be instrumental / PH1 data out in weeks/months)
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