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Oncolytics Biotech Inc T.ONC

Alternate Symbol(s):  ONCY

Oncolytics Biotech Inc. is a biotechnology company. The Company is focused on developing pelareorep, an intravenously delivered immunotherapeutic agent that activates the innate and adaptive immune systems and weakens tumor defense mechanisms. This compound induces anti-cancer immune responses and promotes an inflamed tumor phenotype turning cold tumors hot through innate and adaptive immune responses to treat a variety of cancers. This improves the ability of the immune system to fight cancer, making tumors more susceptible to a broad range of oncology treatments. The Company’s primary focus is to advance its programs in hormone receptor-positive / human epidermal growth factor 2- negative (HR+/HER2-) metastatic breast cancer and advanced/metastatic pancreatic ductal adenocarcinoma to phase 3 licensure-enabling studies. In addition, it is exploring opportunities for registrational programs in other gastrointestinal cancers through its GOBLET platform study.


TSX:ONC - Post by User

Comment by Noteableon Feb 05, 2023 4:00pm
291 Views
Post# 35267872

RE:RE:RE:ONC fair value is $152.36 CDN or $114USD

RE:RE:RE:ONC fair value is $152.36 CDN or $114USDFor comparison Merck announced full year 2022 worldwide sales at $59.3 billion, an increase of 22% from full year 2021.

During 2022, Keytruda sales climbed to $20.94 billion, up 22 percent from $17.19 billion in 2021. Lynparza sales were also up for the full year, hitting and exceeding the billion-dollar sales mark for the first time at $1.12 billion, a 13 percent increase versus $989 million the prior year.

Sales revenues from the sale of Keytruda represented for 1/3 (33%) of Merck's worldwide sales in 2022.

In 2022 Merck's outstanding shares totaled 2.54 Billion shares with Merck's share price peaking at US$115 in January 2023 giving Merck a a market cap of $292.1 Billion.


Sales of Keytruda represented approximately US$ 98 Billion of Merck's market cap.

Given that PD-(L)1inhibitor sales are expected to reach US$67 Billion in the next 4 years, the expected market cap increases of the those companies with immune checkpoint inhibitors would be approximately US$201 Billion by 2027, making this class of immunotherapy drugs a significant segment in the treatment of cancer, from a market perspective. (without the inclusion of ONCY's pelareorep) 

And then considering that ONCY has the potential of increasing the effectiveness of PD-(L)1 inhibitors by 2-3x, those Big Pharma companies that currently possess an immune checkpoint inhibitor would appear significantly interested in acquiring ONCY (pelareorep) given pelareorep's ability to enhance checkpoint inhibitor efficacy while expanding the PD-(L)1 market in the process. Any Big Pharma company seeking to differentiate their PD-(L)1 drugs from the competition while gaining a bigger percentage of the expanded PD-(L)1 market, would certainly be interested in acquiring ONCY for the US$9-10 Billion that the above "fair value" per share figure represents.



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