Sernova Corp T.SVA

CrISPR

[Metalsguy1]

https://www.npr.org/sections/health-shots/2021/06/26/1009817539/he-inherited-a-devastating-disease-a-crispr-gene-editing-breakthrough-stopped-it

[Mudlogger1]

I get using gene editing for deterministic inherited disease...but does that apply to diabetes? Can you gene edit ahead of time or after the fact for lifestyle?  Wouldn't you need to edit for boxes of donuts, buckets of alcohol, lack of exercise? Just asking. The story is incredible and that Irish guy hit the jackpot...just not sure that a brittle diabetic and the multiple factors

[Redbaron2211]

CRISPR isn't a threat to treating TD1. First the gene has to be discovered if it's even a gene that causes td1. It's still a mystery and will likely remain so for some time.

[Metalsguy1]

More ignorance from the peanut gallery. Are you sharing your nuts with mudslinger red? If Gene editing can't be used to address the disease how can the company be using gene editing to protect beta cell transplants.

[Redbaron2211]

Metal there might be some success in treating T1D with gene edited IPSC cells but this only highlights the relevance of the pouch.  To prevent the damage before it happens with CRISPR we would need to know what gene causes T1D.   This is far from clear and most speculate it is a combination of both genetics and environmental factors.   An example being identical twins with

[Metalsguy1]

Red. My point is that with the glacial pace that SVA chooses to follow, even something as challenging as using CRISPR , just about anything is possible. Mudslinger things science is slow but if science were really this slow we would still not have a polio vaccine.

[Metalsguy1]

Obviously, you do have a lot in common with turnips. Type 1 diabetes has nothing to do with lifestyle. It is an autoimmune disease. Since you don't understand the very basic mechanism of type 1 diabetes, I won't waste my time explaining the various pathways that CRISPR could be used.

[Mudlogger1]

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