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Theratechnologies Inc T.TH

Alternate Symbol(s):  THTX

Theratechnologies Inc. is a Canada-based clinical-stage biopharmaceutical company. The Company is focused on the development and commercialization of therapies addressing unmet medical needs. It markets prescription products for people with human immunodeficiency viruses (HIV) in the United States. The Company's research pipeline focuses on specialized therapies addressing unmet medical needs in HIV, nonalcoholic steatohepatitis (NASH) and oncology. Its medicines include Trogarzo and EGRIFTA SV (tesamorelin for injection). Trogarzo (ibalizumab-uiyk) injection is a long-acting monoclonal antibody which binds to domain 2 of the CD4 T cell receptors. It blocks viral entry into host cells while preserving normal immunologic function. The Company is also investigating an intramuscular method of administration of Trogarzo. EGRIFTA SV (tesamorelin for injection) is approved in the United States for the reduction of excess abdominal fat in people with HIV who have lipodystrophy.


TSX:TH - Post by User

Comment by SPCEO1on Jul 17, 2022 10:23pm
106 Views
Post# 34830313

RE:RE:RE:RE:RE:Some thoughts on the financing

RE:RE:RE:RE:RE:Some thoughts on the financingWhile mthat isa good description I can live with, I still think it is probable they get to two responders in one cancer type, particularly if they increase the number of patients to 25 in each of t he four main cancer categories.

qwerty22 wrote:

I'd call it PROBABLE and POSSIBLE. PROBABLE that they have a molecule with anti-tumour activity in humans (based on 1a signs of efficacy). And POSSIBLE that they can hit the number of responders in 1b that triggers go forward to Phase 2 and a registration trial.


palinc2000 wrote:

 You wrote thst a successful Phase 1 b is PROBABLE !Do you really mean that?
I rate it as PoSSIBLE which is what I would have called it after the extensive pre clinical studies...
Maybe we could now describe the chance of success MORE POSSIBLE but imo no more thsn that
 

 

SPCEO1 wrote: We can now have much greater confidence that a successful 1b is probable. But they still have to deliver those goods. I imagine there are a lot of other scientific aspects yet to come out about the trial that will also make the opportuities for partnerships more or less lucrative. 

 


The first $60 million from Marathon is all about the convert. The final $40 million is likely targetting cancer funding. The cost of capital for the debt is likely to always be lower than equity but I am not sure how much money TH will need to get the first phase 2 trial completed. When added to t he normal cash burn they already have, I think they will need to raise some equity capital too, but that will also depend on the timing of partnership cash they might be able to generate. I am not optimistic they will get a large amount of upfront cash out of China but who knows?

In the end, I think the stock gets acquired by Pfizer or another large pharma if their Sort1+ platform looks as attractive as it seems it has the potential to look. I am not sure how long that takes but if IMMU is an indicator, they need to get the first cancer type approved before big pharma is willing to pay up for it.  

 

TH1902 wrote: great post, thank you SPCEO, after a long journey its pretty incredible that the future of Thera lies in the katana acquistion by Luc  What stood out to me about your post was that TH1902's success/failure defines the future for Thera. 

I wonder what Marathon saw that yielded the $100M deal? A successful 1b goes a long way to re-defining our future...I pray for that! 
SPCEO1 wrote: The cancer data was the critical info last week but the financing deal was very important as well, so let's look at little more at that too:

1.) $40 million to be taken down shortly at a rate of just over 11%

2.) $28.5 million of that will be used to repurchase $30 million face amount of the convert, leaving anoter $27 million outstanding. 

3.) Interest costs will start off at roughly $367,000 per month ($4.4 million per year) for the new loan but  will almost certainly rise as the SOFR rises with the general level of short term interest rates. This will only impact 1 month of Q3. Of course they will still be paying interest on $27 million in convertible debt for the next three quarters too or roughly $1.2 million on that.

4.) So, $11.5 million of extra money from the first tranche added to the say $27 million they probably already have at this point for a total of $38.5 million in cash on hand. 

5.) But $27 million is committed for paying off the remainder of the convert (assuming they don't have great data between now and June  that causes the world to suddenly fall in love with the stock and push the stock above the convert's $14.80 conversion price). So, after taking that into consideration, cash is just $11.5 million.

6.)  Of course, that is where the second tranche of $20 million by June of 2023 comes in. So, adding that back in, we get to $31.5 million less any additional cash burn between now and then. Let's peg that cash burn at $4 million a quarter or roughly $12 million. So, by the time they take down that second tranche, they will have roughly $20 million in cash on the  balance sheet. This assume they have not started a phase II trial.

7.) I am going to go ahead and assume an interest rate of 13% on the loan by the time the second tranche is taken down which brings the yearly interest bill to $7.8 million post June 2023 or about $650,000 per month.

8.) TH is incentivized to take the third $15 million tranche by December 2023 in order to extend the period where the loan is interest only to three years and to extend its term from 5 to six years. As long as the company meets the milestones, I have to believe they are drawing this down too. And assuming no huge influx in cash from partners, they will need the money too.

9.) Now, we have to assume TH will be in a phase II trial by June 2023. If somehow TH-1902 flops in phase 1b, then things get ugly pretty quickly. If not, and a phase 2 trial is started, then that means the outlook for the drug is pretty good, and the opportunity for partnerships, and the upfront cash that comes with it, will have expanded very significantly. So, maybe they never draw that third tranche or even the second tranche. Maybe they even pay off the entire Marathon loan at the end of two years before it moves into a principal and interest payment because they are suddenly cash rish? Moreover, if they are in a phase II trial, maybe they have already gotten a BTD from the FDA for TH-1902. It is not hard to see them raising more equity off of a much higher share price at that time and starting to look like a more standard overcashed biotech company. That's a lot of maybes, but you get the idea. Good clinical success begets increased financial flexibility on better terms. 

10.) THTX is about to turn the corner into such good clinical success. It if successfully completes that turn, the loan will likely become an afterthought among investors. If they don't, TH's finances will get very strained and they will be deperately looking to raise cash at bad equity and partnership prices while trying to restart their cancer efforts with a new version of TH-1902.  

 

 

 




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