RE:RE:RE:RE:RE:RE:RE:RE:RE:RE:Well?Thanks again. I will read more about that to see if I feel safe trying it. I already lose 2 pounds per month since the start of this chemo last March. This chemo is called captem (capecitabine/temozolomide), two old generic drugs and the temozolomide hits quite hard. Also I take the highest dose of somatulin, an analog of somatostatin, which has the opposite effect of GRF or Egrifta. GRF is also called somatocrinin. So somatostatin analogs are decresing secretion of growth hormone and then IGF-1 and all that pathway. So one of the benefit of fasting I already have through that drug. But I may try it anyways. The result of my next scan will tell me a lot about where I am with the cancer and the effect of the chemo. Again, thanks for the info.
juniper88 wrote: We had done a lot of research on this topic. There is a lot of disinformation on the internet too. Like the idea that you can starve the tumors. That is not what intermittent fasting is doing. What you want to do is to at least achieve autophacy, i.e., your body start to consume the not so healthy immune cells to be recycled. Then when you start eating again brand new immune cells are create that are more able to fight diseases. We found that a 3 day fast seemed to be optimal for my wife, but basically autophacy starts after about 18 hours.
It really is not as difficult to fast as you might think. I did a couple of 5 day fasts to support my wife emotionally when she fasted. And one time she did a 17 day fast. She felt fine but it did not slow down the cancer at according to the CA-125 blood tests she was taking. Basically, hunger comes and goes, it does not get worse and worse.
jfm1330 wrote: Hi Juniper,
It's my last day taking chemo pills in this cycle, after that I will have 14 days off. I will have a scan in the next two weeks, so I will look into it and maybe start trying it in my next chemo cycle. Thanks for the link.
juniper88 wrote: My heart (and my prayers) goes out to you and your dad. I don't like to give advice to people, but I would like to make you aware of something that might help your dad. My wife tried intermittent fasting while her oncologist was monitoring her cancer marker. It slowed down her cancer. Her WBC increased once she stopped the fast and that seemed to slow down the cancer growth. I wish we had known about this a bit earlier as she didn't try it during cancer chemo treatment before she went experimental.
Intermittent fasting has shown benificial during chemo treatment. It can be as simple as not eating (still dring water and take all medicines) for about 24 befort the chemo treatment.
https://pubmed.ncbi.nlm.nih.gov/34788373/ I am sure you can Google for a lot more info.
PWIB123 wrote: Appreciate the prayers SPCEO1. Dad started chemo again finally Tuesday this week, so now we wait and see how he responds. Prayers are coveted. This is dad's second time having Stage IV high grade neuroendocrine rectal cancer. MD Anderson wants him to receive 4 treatment cycles before they reassess to decide if the current treatment regiment should be modified. MD Anderson couldn't believe the cancer responded to the treatment dad received back in 2015, because of the tumor type. I know it was a miracle and not the chemo, but they are trying the same chemo treatement again, even though they admitted that they wouldn't have initially prescribed it due to be neuroendocrine.
I've never understood what seems to be an inordinate amount of time for the blackout excuse to be used as to why insiders may not be buying. It does make sense now that financials are being prepared, but not necessarily over the last 60 days. I suppose they could have some major announcement coming that would forbid them from trading, but I would be surprised.
How can investors find out what the company policy is around blackout periods?
https://www.naspp.com/blog/4-Trends-in-Trading-Blackout-Periods