RE:RE:Good discussion boys
I think that 20-25 patient data threshold is out of date. I believe that when they had the 2/3 CR's in the phase 1b they were told that IF the data continues to look this good over time then 25 patients would be sufficient. 66% CR carried forward to 450 days would be good enough.
Then came the undertreated patients and the CR's changed so all bets were off.