Theralase Technologies Inc. V.TLT

Newsletter out

[Oilminerdeluxe]

Is it worth reading it?

[Oilminerdeluxe]

Guess it was... "The Company is preparing to launch a fifth Canadian clinical study site later in 4Q2020. Theralase® is in advanced discussions to launch a number of U.S. based clinical study sites in 4Q2020, subject to the United States economy recovering from the COVID-19 pandemic. The U.S. based Trial Management Organization (“TMO”) plans to launch 4 to 5 clinical study sites in

[Oilminerdeluxe]

Out of the 7 patients that are eligible to receive the second treatment, 6 have received the second treatment and 1 is pending in 4Q2020.

[IvanVanBeethoven]

Here 's the link: https://theralase.com/wp-content/uploads/2020/10/Quarterly-Newsletter-3Q2020.pdf

[Oilminerdeluxe]

If successful, Theralase® will commence GLP toxicology studies in 2Q2021 with an aim to commencing a Phase Ib clinical study in GBM and NSCLC in 4Q2021.

[StevenBirch]

That seems like the only 'news'.

[enriquesuave]

An extra 2 patients who are showing negative cystoscopy but positive cytology are still pending as UUTUC has not yet been ruled out and may be CR as well. Looks like they are aiming to start a trial for both GBM and NSCLC as that would make sense if they are using X-ray activation.  We will hear of preclinical animal data before.  IMO. The hospitals are screening new patients hopefully

[Thor6570]

Has our drug not passed Safely already. Why another phase 1 for Covid ?

[goldn1]

different indication, different trial thor... looks like their gonna list to nasdaq tho :)

[tdon1229]

In answer to Thor, the company needs to determine how to administer the vaccine to humans safely and efficaciously.  Currently, we only have safety data on bladder instillation. Note that Study II completion is now approximately 3 years, consistent with treatment of patients in years one and two and one year for demonstrating CR for those yet to be treated.  If completion means total N

[Hempdoc]

  We could still possibly have a 42% CR...not bad for all having been under treated.  Also, the 4 patients that had been withdrawn from the study due to not showing a response (based on the original/more stringent protocol) would have been eligible for a 2nd treatment based on the updated protocol...all 4 had shown stable disease (no disease progression).  So "92%" of

[Pandora]

Based on market performance today - down a penny to 13.5 cents, setting a new 52 week low -- it seems the market in general did not get the same positive vibes, but I guess we will have to write it off as just a bad day on the overall market - couldn't be company specific.

[riverrrow]

Move along folks. Nothing to see here.

[Bunge]

I bought too soon.

[Oilminerdeluxe]

We all did. Although, this update at least feels like a step forward. But the waiting part is just soooo long.

[NeilPaert74]

It looks to me like everything is going smoothly now, acording to this newsletter. I don't like that they didn't mention FDA BTD or Fast Track, one of which I thought is pending? Also, The Covid 19 mess slowing down our Phase 2 enrollment. Everything else was perfect. That 3 yr wait assumes no FT or BTD, either of which c(sh)ould lead to Accelerated Approval(Commercial Product) by late

[langosta1]

Theralase® is in advanced discussions to launch a number of U.S. based clinical study sites in 4Q2020, subject to the United States economy recovering from the COVID-19 pandemic

[StevenBirch]

Langosta I understand you skepticism but things can and are changing on a daily basis.  Just today AstraZeneca "says it's vaccine produces an immune response in older adults". They go on to say that the immune response is similar to that in younger people and adverse responses to the vaccine were lower in older people. They hope the vaccine can be developed before the end of

[goldn1]

they have been in advanced discussion w tmo for 1.5 years... no reason tmo can't sign multiple hospitals and have enrollment to start when covid 19 concerns are gone. Fast track would have been welcome news, but I don't c it coming it tlt can't prove it knows how to treat patients effectively and consistently

[riverrrow]

[riverrrow]

No new patients have been treated in Canada. With new covid cases at new peak levels in Canada and the US don't expect any new patients to be tested any time soon. At the most optimistic patient 25 might be treated December 2021, with the one year mark at December 2022 and results released sometime in early 2023. If you know who wins in the US expect the push for full lockdown until the virus

[jojomarch]

What I understood from this newsletter is that we depend on many uncertainties . The expenses have been cut but not the.founder and his wife , such a move would show that you care about the company and its shareholders . From past experience , TLT has not often respected timelines why should I expect anything different. They have been consistent with issuing cheap shares , I think it should be