Theralase Technologies Inc. V.TLT

Photodynamic therapy combined with immunotherapy: Nov 15/23

[Oden6570]

Photodynamic therapy combined with immunotherapy: Recent advances and future research directions - ScienceDirect

[N0taP00p]

This to me, is the Holy Grail for Ruvidar.  Long research paper but glanced through it.. Even standalone,  the results have been great but when combined with an immunotherapy, should get amazing results.. The perception of lingering side effects needs to be overcome.   Even vaccines are mentioned in this paper.    But first, let's hope they get enough money to

[N0taP00p]

Plus, this paper has SO many photosensitizers mentioned.  A lot of them still seem to be in animal studies mode.  Photofrin is mentioned. Couldn't find references to Ruvidar.  I'm sure it's in there somewhere.  

[Jaro1977]

We are mentioned; Ruvidar® (TLD-1433) ruthenium-based coordination compound 532 – 0.35–0.7 mg/cm2 Lung cancer, melanoma, non-muscle invasive bladder cancer [135] Reference S. Chamberlain, H.D. Cole, J. Roque 3rd, D. Bellnier, S.A. 

[Rumpl3StiltSkin]

Did they mention that Ruvidar is an immunotherapy? And that it has none of the PDC specific side effects? Or any adverse effects...? Still under the radar, for now.

[Eoganacht]

In case anyone missed it, Theralase applied for a new patent last month:  https://stockhouse.com/news/press-releases/2023/10/05/theralase-r-files-us-patent-for-enhanced-immunotherapy "...Theralase® announced that it has filed a US patent, titled "Enhanced Immunotherapeutic Method Comprising Combined Administration of Photodynamic / Radiotherapeutic Compounds and

[Longholder99]

While we await these huge moves for a small company started by an Engineer with huge foresight.  We can and should consider and imagine the relief felt by these first patients living with healthy cancer free bladders that were headed to biohazard disposals.  Bless this company and its supporters. To those who badmouth and seek to drag it down.  Shame. 

[Alamir1111]

Ok Long nice ..what would be the reason that tlt got no recognition from investment companies? Most small biotech got 15 to 25 investment co lined up .some have up to 100millions in cash...doing phase 1 snake oil?Hint Its not tsx exchange

[Eoganacht]

Good post Longholder99. In terms of patient welfare, it's gratifying to compare Adstiladrin's performance with that of Ruvidar PDT Of 103 CIS patients treated with Adstiladrin 24 of them still had a CR 15 months after their initial treatment. If Ruvidar PDT maintains only the current 33% CRR at 15 months this will mean 33 CR patients at 15 months. So for just the first 100 patients

[DeathXray33]

Very well said... @>1.191 million now...