Antibe Therapeutics Inc(Pre-Merger) ATBPF

Healthcare

Antibe Therapeutics Inc. is a clinical-stage biotechnology company. The Company is leveraging its hydrogen sulfide (H2S) platform to develop therapies to target inflammation arising from a range of medical conditions. The Company’s pipeline includes assets that seek to overcome the gastrointestinal ulcers and bleeding associated with nonsteroidal anti-inflammatory drugs (NSAIDs). Its lead drug, otenaproxesul, is in clinical development as an alternative to opioids and NSAIDs for acute pain. Its second pipeline drug, ATB-352, is being developed for a specialized pain indication. The Company also focuses on inflammatory bowel disease (IBD). Otenaproxesul combines a moiety that releases hydrogen sulfide with naproxen, a non-steroidal, anti-inflammatory drug. ATB-352 is an H2S-releasing derivative of ketoprofen, a potent NSAID commonly prescribed for acute pain. Its IBD candidates are being designed to maintain the efficacy, safety, and pharmacokinetic properties of ATB-429.

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Antibe Therapeutics Inc(Pre-Merger)

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NicOx Shutters HQ After Approval Fail

FDA issued a complete response letter to NicOx in late July denying approval of the osteoarthritis treatment and demanding more long-term clinical studies to determine cardiovascular and gastrointestinal side effects. The treatment did meet FDA’s efficacy criteria, however, according to NicOx. An FDA advisory panel recommended that regulators deny approval in May, causing NicOx’s stock to crash. The stock dropped even further on July 22 when FDA made its response public.

https://www.pharmexec.com/nicox-shutters-hq-after-approval-fail

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