Theratechnologies Inc T.TH

Omicron

[jfm1330]

I fear this new variant will mess up a lot of things in the coming months. This variant is three to four times as contagious as the delta, and as virulent. We will very likely end up with shutdowns in many sectors. Here in Quebec our vaccination rate for the 12 years old and older is 90%, and this thing is rising sharply and Omicron is still not the dominant variant. So imagine in the US in many states where the vaccination rate is much lower. I fear it could be worst than the first wave.

[realitycheck4u]

This post has been removed in accordance with Community Policy

[SPCEO1]

While I tend to agree that we should not be in an alarmist mode over Omicron until such time as we see a lot of hospitalizations occurring because of it, the math still looks worrisome even if it does not cause a lot of serious illness. That is simply because of how many people will get it. It is breaking through triple vaxed people and people who were infected before. So, there is a very good

[realitycheck4u]

This post has been removed in accordance with Community Policy

[jfm1330]

The problem with omicron, again, is that it is three to four times more contagious than delta, but as virulent. Yes the vaccine will not protect very well against catching it, but with a third shot it is still very efficacious at preventing severe illness, hospitalizations and death. The problem lies in the unvaccinated people. This time around, the unvaxed are much less likely to avoid it

[jfm1330]

Also, to our friend who thinks covid is like the flu. Here in Quebec (population 8.5 M) we have a mean of 4 deaths per day, with 90% vaccination rate in the 12+. If we were the US (population 330 M$), it would mean 155 deaths per day. Compare that with the reality of the mean number of covid deaths in the last seven days in the US which is 1300 deaths per day. This is very sad. So many Americans

[SPCEO1]

The evidence we have so far mostly suggests that Omicron is far less virulent as Delta. Let's hope it stays that way. But, as I said, even if it does, the math is still hard to get around. More infections, even with less virulence, will still cause a lot of problems for hospitals and they have enough problems already in many places dealing with the consequences of the Delta variant in the

[jfm1330]

Out of a recent study made in the UK, there is no evidence omicron is less virulent than delta. This early impression of lower virulence came from South Africa where the population involved was much younger. What I heard from virologists here in Quebec is that omicron is very likely to be as virulent as delta, but much more contagious, but again, the main problem is for the unvaccinated (two or

[jfm1330]

I also disagree and the unpredicatability. The emergence of a variant like omicron was very predicatable, and you want another prediction? There will be another variant that will totally escape the protection of actual vaccines. The only possible positive aspect of omicron is that it is so contagious, that so many non vaccinated people will get it, and many will die because of it, but so many

[qwerty22]

Ghoulish! positive = many will die

[qwerty22]

[qwerty22]

[Wino115]

I'm not that worried as Paxlovid is on it's way in 2 months. It cuts the risk of hospitalization for anyone by 90% and it is supposedly variant agnostic given how it works, which is different from the vaccines that stimulate your immune system.  They are evidently ramping up production so it will be available in 2 months time given it's a very complex manufacturing process. 

[SPCEO1]

Increasingly, it looks like Omicron will sweep through much of the population before  paxlovid arrives. Now, it also looks like Omicron may already be peaking in South Africa - let's hope it burns out faster than expected.

[Wino115]

The White House went all out with the scientific facts today and was pretty blunt about where we are. I had to actually look up the transcript to see if this quote was correct, and it was. It's up to states, but many will make "normal" things tougher if you aren't vaccinated.  It already is in many places now. In NYC, it surprises tourists that you can't even get in to a

[scarlet1967]

The problem is despite known facts the authorities round the world didn’t deal with the covid19 correctly, panic/greed but certainly not lack of understanding could be the cause of all those missteps dealing with pandemic and still is. RNA viruses tend to mutate more frequently the process starts with the virus enter the host’s cell copy itself enter more cells more copying and entering more cells

[gamakichi]

America is the land of the FREE and the home of the BRAVE. Making life hard for those who choose not to get a vaccine is antithetical to the American way and erroneous on many levels. If you can still transmit the Virus to others even after vaccination the only argument to get it is if you are afraid of potential negative repercussions for yourself. Forcing it on individuals is ridiculous. I'

[longterm56]

Surely you don't believe that "American freedom" means anyone can do anything they want. That's not freedom, that's chaos... kind of what we have now. ;) -LT

[Wino115]

Do you also decide to drive when you're drunk because you are FREE to do so?  Is that also a risk you are willing to take, but putting everyone else in danger?  You do know the concept of the public common good, right?  In your world, small pox is still alive and dangering the lives of every child in the world. Right, THAT'S the world we all want to live in! The point is

[gamakichi]

Wino, First I have a ton of respect for you and everyone else here. I do believe driving drunk is wrong due to the individuals impaired cognitive and physical function. Much different conversation. I have multiple friends who have never been vaccinated. Their parents chose to homeschool. I say good for them. I was vaccinated bc my parents made that choice and that's fine too. 

[qwerty22]

The Covid vaccine has been a political football both sides have kicked about. Pre-election when Trump wanted rapid progress on the vaccine front the Democrats were labelling it a potentially dangerous 'Trump vaccine'. In Europe their woes about supply chains and early panic about blood clots had centre politicians jumping one way then the other on the value of certain vaccines. Even just

[palinc2000]

Biden won the last election for one and one reason only,He said ,,I WILL SHUT DOWN THE VIRUS,,,,,, Kamela Harris told americans during the campaign she would not trust a Trump vaccine... Personnally I think  everyone should  get vaccinated but  the fact that its not mandatory  simply means that its a personal choice,,,Demonizing  against the unvaccinated is the wrong

[scarlet1967]

The decision should be left to individuals but some need guidance to make an educated decision during confusing times and misleading media isn't it. Wino's DUI is very obvious most folks get it but again comparing a deadly very unpredictable disease with much very different common viral infections is wrong. You and most infected patients do survive but every and each lost life is

[Kd5513]

Well said and spot on........a little thing called freedom which we in the US still have a little bit of. Sadly, however, we will have 2-3 months of languishing waiting on THTX due to morons in the power of govt.

[jfm1330]

Freedumb!!!! Vaccinated people have much less risk of catching the virus in the first place. So transmition is much lower in a highly vaccinated population. I am so tired of crazy anti-vaxers. Also, wanting to be free to die is quite idiotic. Wanting more people to die in the society is so selfish and dumb.

[Kd5513]

Not anti vax, just common sense. Not making light of the disease do what you and your DR have talked about based on your situation. Definition of vaccine: a substance used to stimulate the production of antibodies and provide immunity against one or several diseases, prepared from the causative agent of a disease, its products, or a synthetic substitute, treated to act as an antigen without

[jfm1330]

Freaking idiocy! High vaccine rate in a population means much lower mortality rate. We see it in real time. I gave this example yesterday. Here in Quebec (8.5 M population) we have a 90% vaccination rate in the 12+, and we have 4 deaths per day on average. That would be 155 deaths per day in the US (330 M population). But the US only has 71% of the population over 12 fully vaccinated (two doses

[Kd5513]

Is every example of death related to an unvaxxed individual or traced back to unvaxxed???? NO! so you have no argument on everyone needs to do their part as those who got the jab are just as much of a threatas those who didnt. The vaccine is weak and does not do what it should in providing immunity but you can continue being a sheep and blaming those who dont want it for personal choice or

[jfm1330]

Stop your freaking disinformation! I showed it clearly comparing vaccination rates between Quebec and the US and mortality outcomes. The US government said it clearly recently as cited by Wino. For the unvaccinated, you’re looking at a winter of severe illness and death for yourselves, your families, and the hospitals you may soon overwhelm. The more people get vaccinated, the less severe this

[palinc2000]

https://apple.news/AaXaR2oWpTHCQnEilvmgCtQ quote=jfm1330]Stop your freaking disinformation! I showed it clearly comparing vaccination rates between Quebec and the US and mortality outcomes. The US government said it clearly recently as cited by Wino. For the unvaccinated, you’re looking at a winter of severe illness and death for yourselves, your families, and the hospitals you may soon

[qwerty22]

In 2020 UK deaths went up by 100,000 over the usually annual rate. The number of cancer diagnoses went down by 50,000. Those cancers did not go away, they just didn't get diagnosed. Many of those will turn into deaths. That's just one disease category. The virus is here to stay. We are all-around not living healthily with this virus. The unvaccinated are not using the best tool there is

[jfm1330]

I was giving the example of Quebec as something positive with our 4 deaths per day for 8.5 M of population, with 90% vaccination rate for those 12 or older. But imagine if we would have mandatory vaccination (significative fines for the unvaxed), our vaccination rate would be somewhere above 97% and we would not have more than one death per day on average, probably less. We still have 4 deaths per

[Wino115]

...and the ability of more bodies to work as petri-dishes for the next more transmissable and more severe version, which will ultimately end up as something perhaps as deadly as something like Ebola according to the WMA. Even if a vaccine isn't 100% at keeping it out (but still 100% at living thorugh it), it still minimizes the bodies it needs for mutations immensely.

[jfm1330]

The news is just out here, 80% of covid cases in the province of Quebec are from omicron. We got a bit above 5,000 new cases today and 8 deaths. All that with 90% vaccination rate. Imagine what it will do in some states in the US that only have 60% vaccination rate. While taking a walk in a snowy forest up north here, I just listened to a podcast featuring Dr. Eric Topol. He too thinks that the

[muslix1]

i like the football bowl season.. it's going to be a great super spread event this year.. no mask in the stands ouch .. good luck guys..

[qwerty22]

"The Science" says Omicron is milder even if it finds it difficult to clearly say it at this point. This guy whe interviewed on the BBC also said his research was in line with the clinical findings coming out of SA of milder disease. https://twitter.com/SkyNews/status/1472845988893278210  

[qwerty22]

https://www.cam.ac.uk/research/news/omicron-may-be-significantly-better-at-evading-vaccine-induced-immunity-but-less-likely-to-cause Omicron 1) Evades waning immunity. 2) Stopped by booster. 3) Infects lung cells in a different way. 4) Does not induce some pathological changes associated with severe disease. 5) Poor replication and impaired cell entry. Not "harmless", not a

[qwerty22]

It's not called solidarity when it's built by coercion, it's called authoritarianism.  

[qwerty22]

There is no perfect drug. Whether vaccine or other medicine. So holding it up to too high an expectation is problematic. Look at cancer drugs, some get approved on 30% efficacy. The sum total of these imperfect anti-cancer drugs is much, much better outcomes for cancer patients. You can't wait for perfection in order to act. The same is true with vaccines. The imperfections of the vaccines don

[qwerty22]

Maybe he's an anti-vaxxer, idk. I don't read anything anti-vax in his statement though, just the right to choose. Seems everybody is capable of a blinkered views of the world. Being anti coercion is not the same as being anti-vax. If you want to protect yourself get vaccinated then your risk from getting the virus is minimized. The risk other individuals pose to you whether they are

[gamakichi]

Well said QWERTY. Not anti vaccine at all.  Never have been. But do believe it is the individuals decision and nobody else's. Every time this comes up people have nothing better to say than to take shots. I really don't understand why it's so polarizing. The entire point of the vaccine is to save you from potential negative outcomes. Get it if you want to get it or if you

[jfm1330]

This is totally false. Vaccine is not strictly for individual benefit, it is a weapon to stop a contagious disease from spreading and harming others. You take the vaccine to protect yourself, but also others. Smallpox was eradicated through mandatory vaccination. In the case of covid, governments are lacking courage to impose it because it is not deadly enough. Yes, it is crazy to say that, but in

[qwerty22]

Covid will not be eradicated. It's a false expectation. It's now endemic. It spreads among vaccinated and unvaccinated. Smallpox and polio are the wrong comparators. Influenza is probably better. You have voluntary vaccine programs aimed at the vulnerable to mitigated the effect of the disease. You can have an initial round of population wide vaccination to raise the populations immunity

[Wino115]

Given the AZ/Oxford, Sinovac and Russian vaccines are basically useless, the US Gov't should pressure/guilt/force Moderna and Pfizer to now release the patents.  Especially as Moderna's was aided immensely with NIH funding and scientific help. There's also a question if they stole the lipid covering formula from that company one of you posted up here.  But we need to get

[jfm1330]

I agree that they should find a way to scale up the production and lower the costs, but if every biopharma company should give up patents because the discovery was made with government money, Thera would be in a bad spot, tesamorelin and SORT1 are out of universities's labs here in Montreal.

[qwerty22]

Here is we're the UK is at. Still waiting for data. From BBC website today. Seems to me "experts" find it harder to deliver good news out of fear of being labelled irresponsible. "Ministers wait for crucial Covid data Jim Reed Health reporter, BBC News Last week, public health officials said they would need to see at least 250 hospital admissions

[SPCEO1]

I did see that claim of similar virulence from the UK study but the reputation of that group is not great in my mind as they were way off the mark in some of their earlier predictions on covid. And there really was just one line in a report about it and no data. There have been increases in hospitalizations in South Africa but far less than in previous waves. In the UK, there was a somewhat

[qwerty22]

Don't expect a politician's retreat from a panicked position to look rational or dignified.